San Francisco 49ers quarterback Jimmy Garoppolo had his best fantasy game of the year so far in Week 6 against the Los Angeles Rams. He threw for 268 yards and three touchdowns without any turnovers. This week, Garoppolo faces a tough New England Patriots Defense allowing just 22 points and 219.8 passing yards per game. Garoppolo will have most of his primary weapons healthy for the game, apart from the team's No. 1 back Raheem Mostert (knee). As a QB2 option, you could do worse, but a defensive battle might be in store, which would of course really limit Garoppolo's ceiling. Start him as a QB2 if you don't have any better options, but don't expect a repeat of his Week 6 showing.